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Spectral methods for the solution of a boundary value problem of an ordinary differential equation are reviewed with particular emphasis laid on pseudo-spectral collocation method. The pseudo-collocation method is then used to solve the one dimensional bio-heat equation with metabolic heat generation in cylindrical coordinates applied to human tissue. It was noticed that an increase in heat transfer coefficient (hA), enhanced the temperature but a decrease in the tissue thickness was observed when this coefficient was increased. The effects of the combined heat transfer coefficient are analyzed and the results indicate that the obtained solution can be used in the study of the thermal behaviour of a biological system with the potential to locate tumours in the living tissue.

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